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It is also conceivable that gene therapy may reach a level that allows for a broad clinical application in 50 years from now

The targeted suppression or blockage of NADPH oxidase 2 (NOX2) function significantly alleviates oxidative damage in the retina, corrects immune system imbalances, prevents damage to the inner bloodretinal barrier (iBRB), and mitigates neurovascular unit (NVU) impairment

The enhanced mitochondrial function and the reduced neuroinflammation are the underlying mechanisms