It has also been reported that liraglutide increases neural stem cell proliferation and neuronal differentiation in the APP/PS1 neurodegenerative disease model (Parthsarathy and Holscher, 2013a)
Semaglutide, dulaglutide, liraglutide and tirzepatide had risk of diarrhoea, constipation, and decreased appetite in the comparison to traditional antidiabetic drugs
Safety and Clinical Considerations Gastrointestinal adverse effects The most common adverse effects of incretin-based therapies are gastrointestinal, including nausea, vomiting, diarrhea, constipation, dyspepsia, and abdominal discomfort
Experimental findings indicate that Lp(a) can promote calcium deposition in the arterial endothelium by inducing the chondro-osteogenic differentiation of vascular smooth muscle cells (VSMCs) [67]