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An untreated vitamin B12 deficiency can lead to neurological problems or pernicious anemia, which occurs when your body doesnt have enough B12 to produce the amount of red blood cells it needs ( Vitamin B12 shots are typically the most common way to prevent or treat a deficiency

This nuclear presence of FOXO4 seems to be involved in maintaining the viability of senescent cells by possibly modulating downstream senescence-associated pathways, detailed by changes in p53, Ser15-phospho-p53, and p21 protein levels

More importantly, FSK mitigated excitotoxicity and improved the learning ability and memory in mice [76]

Further, overproduction of free radicals have also been shown to occur due to spontaneous breakdown (autoxidation) and/or excessive metabolism by monoamine oxidase of adrenaline, noradrenaline and dopamine, which can further overwhelm the brains antioxidant systems (Cohen, 1984