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According to available research, weight loss on metformin does occur, though the medication likely wont produce dramatic results

Your BMI is 30 kg/m or above (or 27+ with a weight-related comorbidity including PCOS/PMOS itself) You have insulin resistance confirmed on blood tests or strongly indicated by your PCOS/PMOS picture Lifestyle changes and/or metformin havent produced sufficient results Youre not pregnant and not planning to conceive in the near term (stop Mounjaro at least 2 months before trying) You have been assessed by a clinician, including relevant blood testing Mounjaro can make a meaningful difference

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