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The discovery that bacteria use secretins as the OM gate for EPS secretion prompts the question whether this mechanism represents a completely novel type of EPS secretory pathway, or whether the secretin is used as the OM component of other, already known, EPS secretion systems 7,30

An oral semaglutide formulation does exist, but it needs a special absorption enhancer and careful dosing conditions to survive

Regardless of form, sustained use appears more important than any single dose