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doi: 10.1007/s00223-021-00911-7 123 AtarashiKTanoueTShimaTImaokaAKuwaharaTMomoseYet al

It stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite resulting in improved blood sugar control and significant weight loss

When contrasted with a placebo group and other active comparators, Tirzepatide consistently showed greater efficacy in reducing body mass index (BMI) and improving obesity-related comorbidities, including cardiovascular disease