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It is associated with hyperproliferation and dysfunctional differentiation of keratinocytes

And when we've done some modelling, Norman, to get back to one of your earlier questions, we've been able to show that there are some cancer treatments which offer fairly small improvements in overall survival, and when we've counted up the number of home days versus healthcare system days, it becomes almost a toss-up, that almost every added day of life is traded off by a day with contact with the healthcare system

Enthusiasts of reconfigurable atomizers are well aware of this phenomenon

Nicotine dependence and social norms surrounding behaviour smoking, then, constitute both preconditions and consequences of individual smoking behaviour