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Neuropsychiatr Dis Treat 6:159 Wijekoon EP, Hall B, Ratnam S, Brosnan ME, Zeisel SH, Brosnan JT (2005) Homocysteine metabolism in ZDF (Type 2) diabetic rats

While these results are encouraging, larger trials in broader patient populations are needed to confirm its effects

Yunger, S

b Novo Nordiskdefined hypoglycemia: a severe hypoglycemia event or an event where laboratory or self-measured glucose calibrated to plasma was 15 years Episode of hypoglycemia e within previous 12 weeks Treatment arm 1 Treatment arm 2 Full treatment period: 64 weeks A1C NONINFERIORITY IN BOTH TREATMENT PERIODS WAS A PREREQUISITE Primary endpoint (noninferiority) was achieved, then tested for superiority: Tresiba demonstrated superiority vs insulin glargine U-100 in terms of rates of severe or BG-confirmed symptomatic hypoglycemic episodes during the maintenance period