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Consider pausing other regenerative therapies concurrently to avoid over-removal of senescent scaffolding cells

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These results show how misleading animal experimentation can be in terms of human health and emphasize the necessity to study the specific human disease in detail first and, on this basis, select the cost-appropriate, technologically advanced human-relevant model or method (e.g., use of isolated cells and tissues, organoids, robotics, computer bio-modeling) and system of testing before starting the research (312)

A phase I/IB, open label, dose finding study to evaluate safety, pharmacodynamics and efficacy of pembrolizumab in combination with vorinostat in patients with advanced prostate, renal or urothelial carcinoma