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Morning: Gentle cleanser Vitamin C serum (allow full absorption) Hyaluronic acid serum Niacinamide (optional, can be in moisturizer) Moisturizer Sunscreen SPF 30+ Evening: Oil cleanser (if wearing sunscreen/makeup) Gentle water-based cleanser Copper peptide serum Additional peptide serum (optional, like Matrixyl ) Heavier moisturizer or night cream This routine separates vitamin C (morning) from copper peptides (evening) while delivering multiple anti-aging mechanisms

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Beyond mediating outer mitochondrial membrane fusion, Mfn1/2 participates in mitophagy regulation, mitochondrial cristae remodeling, and facilitates stress-associated unfolded protein response (UPR) (Tokuyama and Yanagi, 2023)