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In one study, 178 patients with stable coronary artery disease took either 1,807.5 FUs of nattokinase, 4.5 grams of monacolins (active compounds from red yeast rice), a combination of 1,830.9 FUs nattokinase and monacolins, or placebo twice daily after lunch and dinner for 90 days

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The peptide's effects on hormonal systems, particularly growth hormone and cortisol, may have implications for certain conditions

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