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By preventing this, DPP-4 inhibitors enhance active GLP-1 and GIP levels by 2 to 3-fold following a meal ( GLP-1 Receptor Agonists Two classes of GLP-1RAs have been developed based on the exendin-4 molecule and human GLP-1 ( The pharmacodynamic effect of GLP-1RAs on glycemic control differs between short-acting and long-acting preparations

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On top of its important role as the powerhouse of the cell, these organelles are also essential regulators of cellular metabolism, redox state, intracellular calcium signaling, and programmed cell death mechanisms [12,13,14,15]