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However, another meta-analysis including 13 RCTs found that GLP-1RAs had a neutral effect on the occurrence of AF in populations with obesity or overweight and without diabetes [31]

The experimental animals were randomly assigned to the vehicle group and TB001 group after transplantation

Whether this translates to humans is unknown , decades of GLP-1 agonist use have not produced a clear signal of elevated medullary thyroid carcinoma risk in post-marketing surveillance , but the FDA has not removed the warning