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Seek emergency care if: you experience severe abdominal pain radiating to your back (possible pancreatitis), persistent vomiting that prevents hydration for more than 24 hours, signs of severe dehydration (fainting, confusion, dark concentrated urine), or if you suspect you administered five or more times your intended dose

Participants in the treatment group paired the medication with a reduced-calorie diet (eating around 500 fewer calories per day) and 150 minutes of physical activity each week