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Therefore, we conducted a target trial emulation using de-identified electronic health record (EHR) data from Optum Labs Data Warehouse (OLDW) to evaluate the long-term effectiveness and safety of GLP-1RA initiation in T1D

Specifically, the activated receptor possibly engages a class of G proteins referred to as Gq/11, which in turn may stimulate an enzyme called phospholipase C (PLC)

One possible mechanism is that DIV-1 may promote GSC maintenance and germline proliferation by maintaining a threshold for germline proliferation/differentiation decision below GLP-1/Notch activity (see Fig

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