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Clove oil or cream that contains extracts of the clove flower is generally considered safe and effective for use on the skin, but the frequent oral application should be avoided as it may damage the gums, tooth pulp, skin, and mucous membranes

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In February 2016, Transport Canada issued a Transportation of Dangerous Goods Safety Advisory 6 alerting air operators, passengers, and crew of the safety risks associated with e-cigarettes and recommended that e-cigarettes, including any associated lithium-ion batteries, only be carried in the cabin