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Improves Heart Health: Research has shown that Metformin reduces the risk of heart disease in people with Type 2 diabetes

doi: 10.1016/j.chest.2020.07.023 48 CuadradoA.PajaresM.BenitoC.Jimnez-VillegasJ.EscollM.Fernndez-Ginset al

RAS-RAF-MEK-ERK MAP Kinases Pathway Stimulation of C-KIT or other receptor tyrosine kinase on the cellular membrane by extracellular growth factors provokes downstream activation of RAS and RAF kinases followed by phosphorylation of MEK and ERK, leading to activation of the MAPK pathway implicated in the regulation of cell proliferation, differentiation, and survival (90)

The latter, therefore, cannot be detected using standard genomic techniques