Excipients q.s
Current prescribing guidance from tirzepatide manufacturers does not recommend routine combination with other weight-loss agents, and most clinicians reserve topiramate for patients who cannot tolerate or have failed GLP-1 monotherapy
Yet anecdotal reports persist, forum threads multiply, and researchers continue investigating possible indirect connections that could explain why some people develop UTIs after starting GLP-1 therapy
doi: 10.3390/ijms20184559 Summary Keywords thiamine, riboflavin, niacin, pyridoxine, folate, cobalamin, complex B vitamins, neuropsychiatric manifestations Citation Han A, Almeida L, Anand N, Salloum IM, Kanaan S, Gadad BS and Daher JPL (2025) Exploring neuropsychiatric manifestations of vitamin B complex deficiencies