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She also noted that the drugs slow down digestion, which could give the stomach more time to break down food and produce gas

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Aromatase, Adiposity, Aging and Disease: The Hypogonadal-Metabolic-Atherogenic-Disease and Aging Connection. Medical Hypotheses , 56(6), 702-708, 2001

Various mechanisms involving alterations in cellular energy charge, AMP-mediated inhibition of adenylate cyclase or fructose-1,6-bisphosphatase 1 and modulation of the cellular redox state through direct inhibition of mitochondrial glycerol-3-phosphate dehydrogenase have been proposed for the acute inhibition of gluconeogenesis by metformin