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We also observed an upregulation of Nos1 (encoding nitric oxide synthase, NOS1) and Ntrk1 (encoding neurotrophic tyrosine kinase receptor 1, TrkA) in this pathway

Population studies have shown that the majority of adults and children with well-documented asthma are atopic, and the prevalence of asthma is greater in subjects with high serum immunoglobulin E (IgE) levels in a close relation with inflammatory cells (1-3)