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Understanding the Hormone Transforming Weight Loss and Metabolic Research In recent years, much attention has been paid to GLP-1 agonists like semaglutide (Wegovy) and tirzepatide (Mounjaro), which have revolutionized the treatment of obesity and type 2 diabetes

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Horton JD, Shimano H, Hamilton RL, Brown MS, Goldstein JL (1999) Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

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