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Tripartite-motif protein 21 knockdown extenuates LPS-triggered neurotoxicity by inhibiting microglial M1 polarization via suppressing NF-kappaB-mediated NLRP3 inflammasome activation

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Epitalon is less commonly recommended for younger adults since the primate studies showed no effect in young subjects, suggesting the peptide specifically addresses age-related decline rather than enhancing already-normal function