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This downward trend in smoking is seen prominently in very young (age 15 to 24) French males and females alike

Most strikingly, nicotine is harmful to developing brains and its use during adolescence can disrupt the formation of brain circuits that control attention, learning, and susceptibility to addiction

More recent work supports this hypothesis, with Shah [69] demonstrating albuminuria and abnormal renal function in tobacco chewers and Gupta et al.[70] indicating that chewers had systolic and diastolic blood pressures, resting heart rates, total cholesterol, LDL cholesterol and triglycerides comparable to smokers

Just top notch work