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Graphical abstract Similar content being viewed by others Background Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by persistent and irreversible airflow restriction, which is related with abnormal airway inflammatory response to harmful gases/particles [1]

Seven Stars (Soft) Seven Stars (Soft) is a limited-edition variant of the renowned Seven Stars cigarette brand, introduced by Japan Tobacco (JT) on October 17, 2023

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This allows damaging stomach contents to wash into the esophagus where they cause pain and increase cancer risk