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And not in a good way

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However, it is thought to be due to imprecise intra-arterial injection leading to arterial thrombosis and subsequently leading to pain, vasospasm, embolism, sympathetic nerve stimulation leading to necrosis in cutaneous, subcutaneous, adipose, and/or muscle tissues.[ , ] Diagnosis is mostly clinical

Namely, unlike BPC 157 native peptide therapy [3,4,5,6,7,8,9,10,11,12,13,14,15,16,17], there is a lacking easy practical applicability for many various growth factors that have been suggested to be necessary for natural healing [23]