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Abstract Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-1), declines over time until only low levels can be detected in individuals aged 60 years

Through its signaling effects, it helps the body adapt to physical stress, injury, and repetitive strain while supporting communication between the gut, nervous system, and musculoskeletal tissues

Both figures are preclinical estimates, not human data